Comparisons

LangChain vs LlamaIndex vs Semantic Kernel 2026

TURION.AI 7 min read
#ai#agents#langchain#llamaindex#semantic-kernel#microsoft-agent-framework#comparison#review#frameworks

Three frameworks dominated the AI agent conversation heading into 2026: LangChain, LlamaIndex, and Microsoft’s Semantic Kernel. But the landscape has shifted dramatically since we last compared them. LangChain is maturing into an agent platform with v1.x, LlamaIndex is doubling down on data infrastructure, and Semantic Kernel has been folded into Microsoft Agent Framework 1.0 GA — a consolidation that changes everything for .NET shops.

We’ve built production systems across all three at Turion. Here’s what’s real in 2026.

The Short Answer

If you’re starting a greenfield project and your stack is Python-first: LangChain or LlamaIndex, depending on whether your bottleneck is orchestration complexity or data pipeline quality. If you’re a .NET shop: you’re all-in on Microsoft Agent Framework now.

LangChain in 2026: The Agent Platform

LangChain has consolidated from a “chain” library into a full agent development platform spanning Python and JavaScript, with tight coupling to LangSmith for evaluation and tracing.

What’s New (April 2026)

Architecture

LangChain’s current structure is organized as:

PackageRole
langchain-coreBase abstractions (models, prompts, tools, messages)
langchainHigher-level chains, agents, utilities
langgraphGraph-based state machine orchestration for agents
langsmithObservability, evaluation, prompt management
langchain-community400+ third-party integrations

The critical insight: LangGraph is now the recommended way to build agents, not the legacy AgentExecutor. LangGraph gives you explicit state graphs with human-in-the-loop support, checkpointing, and conditional edges. We’ve written about this extensively.

from langgraph.graph import StateGraph, START, END
from typing import TypedDict, Annotated
import operator

class AgentState(TypedDict):
    messages: Annotated[list, operator.add]
    current_step: str

def research_node(state: AgentState) -> AgentState:
    # Your agent logic here
    return {"current_step": "research_complete"}

graph = StateGraph(AgentState)
graph.add_node("research", research_node)
graph.add_edge(START, "research")
graph.add_edge("research", END)

app = graph.compile()
result = app.invoke({"messages": [], "current_step": "init"})

Pros

Cons

LlamaIndex in 2026: The Data Pipeline

LlamaIndex’s strategy is clear: own the data layer. While LangChain expands into orchestration and evaluation, LlamaIndex is investing heavily in document parsing, indexing structures, and retrieval optimization.

What’s New

Architecture

LlamaIndex is organized around the data lifecycle:

ComponentRole
llama-index-coreBase abstractions (documents, indices, query engines)
llama-parse / LiteParseDocument ingestion and parsing
llama-index-indicesIndex structures (vector, tree, keyword, summary)
llama-index-retrieversRetrieval strategies (hybrid, recursive, auto-merging)
llama-index-agentAgent abstractions built on top of the data layer
LlamaIndex CloudManaged RAG pipelines and observability
from llama_index.core import SimpleDirectoryReader, VectorStoreIndex
from llama_index.llms.openai import OpenAI
from llama_index.core.retrievers import AutoMergingRetriever
from llama_index.core.node_parser import HierarchicalNodeParser

# Parse documents with advanced node splitting
node_parser = HierarchicalNodeParser.from_defaults(
    chunk_sizes=[2048, 512, 128]
)
documents = SimpleDirectoryReader("./data").load_data()
nodes = node_parser.get_nodes_from_documents(documents)

# Build multi-level index
index = VectorStoreIndex(nodes)

# Auto-merging retriever: retrieves small chunks
# but returns parent context for better LLM grounding
retriever = AutoMergingRetriever(
    index.as_retriever(),
    storage_context=index.storage_context,
)

Pros

Cons

Semantic Kernel → Microsoft Agent Framework 1.0

Here’s the biggest shift: Semantic Kernel as a standalone framework is effectively over. On April 3, 2026, Microsoft shipped Agent Framework 1.0 GA, which unifies Semantic Kernel and AutoGen into a single SDK (Microsoft.Agents.AI) supporting both .NET and Python. (Source)

What This Means

// Microsoft Agent Framework 1.0 — .NET
using Microsoft.Agents.AI;
using Microsoft.Agents.AI.Models;

var kernel = new AgentKernelBuilder()
    .AddAzureOpenAIChatService(
        deploymentName: "gpt-4o",
        endpoint: new Uri("https://your-resource.openai.azure.com/"),
        credential: new AzureKeyCredential("your-key"))
    .Build();

// Plugins are Semantic Kernel's core concept — preserved in Agent Framework
kernel.ImportPluginFromFunctions("WeatherPlugin",
[
    KernelFunctionFactory.CreateFromMethod(
        (string location) => $"Weather in {location}: 72°F, Sunny",
        "GetWeather",
        "Get the current weather for a location"),
]);

var agent = new ChatCompletionAgent(kernel)
{
    Instructions = "You are a travel assistant.",
};

Pros

Cons

Head-to-Head: Decision Matrix

CriteriaLangChainLlamaIndexMicrosoft Agent Framework
Primary strengthAgent orchestration (LangGraph)Data ingestion & retrievalEnterprise .NET integration
LanguagesPython, JavaScriptPython (primary), JS (lagging).NET, Python
LLM supportAny (400+ integrations)Any (broad but smaller set)6 built-in, extensible
EvaluationLangSmith (30+ templates, self-hostable)LlamaIndex CloudDevUI debugger (local)
MCP support✅ Native⚠️ Via community✅ Native at 1.0
Multi-agentLangGraph (explicit state graphs)Custom workflowsAutoGen-style graph workflows
Enterprise readinessHigh (with LangSmith)Medium (community-driven)High (Microsoft LTS)
Best forPython teams building complex agentsData-heavy RAG pipelines.NET / Azure enterprises

Our Recommendation

The choice depends on your starting constraints, not on some abstract “best framework” ranking:

Choose LangChain if: Your team is Python-first and you’re building agents with non-trivial control flow — conditional routing, human-in-the-loop, parallel tool execution. LangGraph is the most mature explicit-state agent orchestration library available, and LangSmith’s evaluation suite gives you production confidence. The ecosystem size means when you hit a problem, someone has already solved it. We use LangChain + LangGraph for building production AI agents across most of our Python deployments.

Choose LlamaIndex if: Your agent’s bottleneck is data quality, not orchestration complexity. If you’re parsing PDFs, extracting tables from presentations, building RAG over legal documents or technical manuals, LlamaIndex’s ingestion pipeline — LiteParse plus hierarchical indexing plus auto-merging retrieval — is the strongest stack we’ve used. Pair it with LangGraph for orchestration; they complement each other well.

Choose Microsoft Agent Framework if: You’re a .NET shop, your infrastructure is Azure-centric, and you need a vendor-backed SDK with LTS guarantees. The convergence of Semantic Kernel and AutoGen into one framework with native MCP and A2A is genuinely compelling — but only if you’re already operating in the Microsoft ecosystem. If you’re Python-first and cloud-agnostic, the vendor lock-in risk outweighs the convenience.

The frameworks aren’t converging into a single winner. They’re specializing: LangChain owns orchestration, LlamaIndex owns data, and Microsoft Agent Framework owns the enterprise .NET stack. Pick the one that matches your bottleneck, and don’t try to force a square peg.

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